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zeegoman
03-15-2004 @ 4:49 AM                           Reply to this Discussion  
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Joined: Mar. 2004
I have been on 150mgs of venlafaxin (extended release) for the past 18 months, for treatment of depression.

I am starting to titrate the dose downward, currently 75mgs. I have had some withdrawal symptoms, which I expected and am coping with however, I have been having what I would describe as breakthrough depression. That is flashes of low mood, with self destructive rumination.

This is exaserbated by even small amounts of alcohol, e.g. a couple of glasses of wine over an evening. (I have obviously stopped drinking alcohol in the interim)

Does anyone have experience of this? I am concerned that I may becoming depressed again. I will be cosulting my medical practitioner about this, but would like other views if available.

squelch
04-13-2004 @ 5:25 PM                           Reply to this Discussion  
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Joined: Apr. 2004
I'm considering a change in meds to V'flexin.   What made you choose to titrate down?  Did you think you had it "solved", or were there side affects?  What was it like for you, and what meds had you tried before.

Good luck as you go through the change/tapering off.

D.

zeegoman
04-14-2004 @ 11:02 AM                           Reply to this Discussion  
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Joined: Mar. 2004
Squelch!

It is recomended that venlafaxine is titrated when you are coming off. This was always the long term plan arranged with my pyhscian. I have however, since returned to the higher dose due to relapse.

I have had many of the tricyclics, SSRI's and SNRI, Fluoxitine, Reboxitine, Paroxetine and Amitriptyline to name but a few, whatever is in vogue. Venlafaxine is classed as a second level drug for more treatment resistant depression.

Until quite recently my depression was distinctly seasonal and I took the drugs for the winter period only.

The main long lasting side effect of venlafaxine has been periodic excessive sweating.

In common with most anti depressants prescribed for depression rather than low mood or blues, it kind of flattens out your emotions, Reducing the occurence, intensity and duration of the lows and the highs. It can also have demotivating effects.

It boils down to whatever suits you in terms of therapeutic effect v side effects. I can live with the venlafaxine side effects but not with some other drugs .

I have NEVER had a Prozac type feel good effect.

Regards

Zeeg Smile

zeegoman
06-24-2004 @ 9:04 PM                           Reply to this Discussion  
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Joined: Mar. 2004
I posted the origional message here. Does anybody else take this ****ed stuff?

I am now taking 225mgs and my life is ****. I have a 2 dimensonal experience of everything. I never feel good, I never feel really bad either in fact I don't feel anything.

There are no highs no lows, nothing. There is no connection with any emmotion.

Is this me or does anybody else identify with this?

please don't give any platitudes coz I've had a belly full!

SaraM
08-25-2004 @ 1:00 AM                           Reply to this Discussion  
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Joined: Aug. 2004
I've been on effexor xr on four separate occasions. OVer all, it's been a positive experience for me. I have a couple of questions for you, though. Did you and your doctor agree that it was time for you to start working down from your initial dose? If you're doing it on your own, you may be feeling residual or breakthrough depression because it wasn't yet the correct time to lower your dose.

If you're feeling nothing, you might want to look into raising you dosage.

Good luck,
sarah

SaraM
08-25-2004 @ 1:07 AM                           Reply to this Discussion  
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Joined: Aug. 2004
Hey,

I've been on Venlafaxine 4 separate times over the past 8 years. Overall, it's been a positive experience. It has some side effects that are difficult to tolerate; for me, the three hardest have been insomnia, diminished appetite, and nausea. ALl three were more or less fixable -- my psychiatrist prescribed me a safe sleeping pill, and so long as I'm on the Ven, I'll be on the pill, as well. Eating, I'm careful to eat most of my food in liquid form, which is easier - yogurt, protein shakes, veg. drinks, etc. The last two times I've been on it (invluding now), I've gotten into a real routine, health wise, and it's worked out well for me.

The benefits, for me, far outweigh the negatives. While I'm taking venlafaxine, I'm functioning. And that's essentially what it comes do. I function normally, I laugh and work and relax and interact with people and the world -- I'm myself. I feel an overarching sense of happiness and contenment.

So, for me, it's been worth it.

Good luck,
Sarah

Ariel
09-01-2004 @ 11:02 PM                           Reply to this Discussion  
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Joined: Sep. 2004
I'm glad you're consulting with your doc. With so many meds out there to choose from, why mess with one that seems to be causing you problems. By the way, I also have problems with self destructive rumination and decreased inhibitions in this area when I drink.

Good luck to you, hope you feel better soon

suzie
09-20-2004 @ 7:46 PM                           Reply to this Discussion  
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Joined: Sep. 2004
i have been taking venlafaxine for a number of years,450mgs, then down to 150mgs, now i'm on 50mgs a day, and its a nightmare, i have suicidle thoughts, cry constantly and all because my doctor wants to try new meds, citolapram, if anyone has heard of these. i felt fine on the ven's but got used to them i think, but the withdrawal for me has been frightening. if these new meds dont work, i have to have electroconvulsivetherapy, which i have had before and believe me,its a living nightmare, i'm at my lowest of the low now and need help, but not getting it, i'm pleased there is somewhere to chat with other people who are experiencing the same problems i am having, thanks for taking time to read this.
suzie..xxx

Barbara
09-23-2004 @ 11:35 AM                           Reply to this Discussion  
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Joined: Aug. 2004
Does anyone know anything about Lexopro? I've just been prescribed 10mg to start two days ago and I feel as if my heart is trying to pound out of my chest. I can't seem to find any info on line.

Josie, Support Specialist
09-23-2004 @ 11:54 AM                           Reply to this Discussion  
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Joined: Mar. 2004
Barbara,

A good idea is to contact your doctor or your pharmacist.  They will be better able to assist you in these medical questions.  Knowledge is power and peace of mind.

Josie

Ouisch
10-15-2004 @ 10:44 PM                           Reply to this Discussion  
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Joined: Oct. 2004
Hi...

I've been taking the lowest dose of Effexor for over three years. For a brief period, I had the dose upped to 75mg, but only for a few months.

Recently, when I tried to stop taking it and switch to another drug, I went through a terrible withdrawal...even though I was slowly tapering off over a month.

I cried constantly. I was also filled with rage, and was terribly confused and disoriented. I got lost and fell down a lot.

I basically just gave up on quitting it, and I'm taking it in combination with my new med now.

I find this highly annoying.

jmc
11-21-2004 @ 12:08 PM                           Reply to this Discussion  
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Joined: Nov. 2004
Hi, I've been on EffexorXL 75mg for about 2 years now and for me, it is the best medication by far of all I had been on. I had medication resistant depression and a "plain" SSRI just did not do it for me. I had also been on Paxil and Remeron, but the Paxil stopped working and the Remeron was really sedating for me--plus there were weight gain problems with both of them. The only very annoying side effect is the sweating, especially combined with menopausal hot flashes, but I think its worth it. The decision to start taking meds was very hard for me too--I guess its that way for a lot of people. I was a nurse, and nurses, like mothers, are not allowed to get sick--especially with something like depression, which is not visible and has no lab tests to help with treatment. I try to think of it as the brain's equivelent of diabetes. In diabetes, the pancreas either can't produce insulin or the body can't use it properly, in Depression, the brain chemicals get all whacked out and I can't think reasonably, I am sure I am incompetent at everything and a burden to everyone. My natural shyness turns into extreme reclusiveness, etc., in a continous, negative downward spiral.
The thing is, with diabetes, they can check blood sugars, but there is no way but trial and error for depression meds, no fun when you are in the "error" end of the equation. In the United States, we have a very "pick yourself up by your bootstraps" way of thinking. We would not expect someone with a broken leg to walk before he got a walking cast on, but we think people with major depression should be able to function as if nothing is wrong.
Even some therapists seem to have fallen into the "well if you would get your thoughts straight, you wouldn't need meds" end of things, which is very frightening to me--it makes me feel that there is no help available if I need it. I can't get my thoughts straight if my meds aren't working, talk therapy helps me keep them straight and deal with messes caused by untreated Depression, but the meds are necessary also.

Kylie
12-20-2004 @ 11:18 PM                           Reply to this Discussion  
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Joined: Dec. 2004
Hi Everyone,
I've never done this before, writing into a computer and hope that someone will respond.
I've been on 250mg of Venlafaxin for four months now and I'm not really feeling any different from all the SSRI drugs I've tried over the past couple of years.  The drug is new here in New Zealand so the Doctors don't really know how long things take and how fast the drug works.  
I'm just waiting for something to change to give me a sign that the medication is working.  I don't know how long to wait before I say something to the Doctor.  What should I be feeling?

zeegoman
12-21-2004 @ 4:13 AM                           Reply to this Discussion  
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Joined: Mar. 2004
You should have noticed some improvement by now. These modern drugs take less time to act than the older ones and you are on a relatively high dose.

Venlafaxine is not a straight forward SSRI it acts on other neurotransmitters as well. It is classed as a second order anti-depressant, that is it is usually prescribed under specialist instruction. It is often prescribed for so called treatment resistant depression which is a bit of a misnoma really because no depression is treatment resistant, its just a case of finding the right treatment.

If you are still feeling depressed then go back to your doctor and tell them. Don't settle for a fob off either. You must not come off the venlafaxine quickly as there are withdrawel effects, both physical and psychological.

I have been on 225mgs of this drug for some time now and my doctor is going to change my treatment in the new year. This is because I have gone as far as I can with venlafaxine.

You should idealy be getting CBT (cognative behavioural therapy) combined with your drug treatment. It is a long haul but don't let the clinicians off the hook. Getting the right treatment is vitally important.

Regards

Iain

Psysick
03-07-2005 @ 10:41 PM                           Reply to this Discussion  
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Joined: Mar. 2005
I was on Venlafaxin for 2 years. 300mg for the majority of that time. I was also on other meds simultaneously for  a lot of this time (1.5 yrs Divalproex,8 months Seroquel). At first I thought venlafaxine was helping my a bit. But I still had my suicidal panics and anxiety and various levels of depression most of the time but not all the time. So now I'm convinced that any effects i was having at first on Effexor were due to me finally getting a psychatrist looking after me. A few months ago I quit the Effexor and Divalproex (quit the seroquel a long time ago).

I think it is kind of sad that all the mental health organizations say that Cognitive Behavioural Therapy is  at least as effective as anti depressants, yet hardly anyone gets set up or refered to a psychotherapist by their family doctor. Don't get too caught up in the "brain chemical imballance" theory. It is just a theory with no proof! Depression is terrible, suicidal ideation is terrible, anxiety is terrible, but don't limit your therapy to only drugs on the basis of some uproven theory.

Posted By Discussion Topic: Venlafaxin -- page: 1 2

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