Tricyclic Antidepressant (TCA)

an older group of antidepressant medications, until recently widely used in the treatment of anxiety and depression. All tricyclics to a greater or lesser extent block the reuptake of serotonin, norepinephreine and dopamine. TCA medications include amitriptyline (Elavil, Endep, Tryptizol, Loroxyl), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin, Pertofran), doxepin (Sinequan, Adapin), Imipramine (Tofranil), maprotiline (Ludiomil), nortryptyline (Pamelor, Noratren), trimipramine (Surmontil), protriptyline (Vivactil).